The Big Bang Theory

Raj's inability to talk to women except when drunk is based on an old co-worker of executive producer Bill Prady when he worked at a computer company.

Mayim Bialik is the only cast member to have a PhD. In 2008, she completed her neuroscience studies. She earned her Ph.D. in Neural Biology.

Jim Parsons audition for the role of Dr. Sheldon Cooper was so good that creator Chuck Lorre immediately asked Parsons to come in for a second one, because Lorre wanted to be 100% sure Parsons was as brilliant as he seemed.