Malcolm in the middle

On the show, Reese is the second oldest brother of Malcolm, but in real life, Justin Berfield (Reese) is less than three months younger than Frankie Muniz (Malcolm).

Aaron Paul auditioned for the role of Francis but lost. He would later be cast in 'Breaking Bad', which also starred Bryan Cranston.

The monster seen rising from the water in the opening credits is the monster from 'Clash of the Titans'.