The Simpsons

The creators jokingly insist that they have parodied 'Citizen Kane' so much that one could re-create the entire film solely from Simpsons clips. They also have made the same claim about 'The Godfather' and 'The Godfather: Part II'.

Although it was believed that Dr. Marvin Monroe was killed off in 1995 (as his tomb stone can be seen in the Springfield cemetery), he reappeared in Los Simpson: Diatribe of a Mad Housewife (2004), in which he tells Marge that he has been "very sick". The real reason for Monroe's relative absence in the series was because he became too much of a strain on Harry Shearer's voice.

This is the longest running prime-time comedy series as well as the longest-running prime-time animated series in US TV history.